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KMID : 0545120220320121506
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Journal of Microbiology and Biotechnology
2022 Volume.32 No. 12 p.1506 ~ p.1514
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Functional Roles of Exosomes in Allergic Contact Dermatitis
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Song Bocui
Chen Qian
Li Yuqi
Zhan Shuang
Zhao Rui
Shen Xue
Liu Min
Tong Chunyu
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Abstract
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Allergic contact dermatitis (ACD) is an allergen-specific T-cell-mediated inflammatory response, albeit with unclear pathogenesis. Exosomes are nanoscale extracellular vesicles secreted by several cell types and widely distributed in various biological fluids. Exosomes affect the occurrence and development of ACD through immunoregulation among other ways. Nevertheless, the role of exosomes in ACD warrants further clarification. This review examines the progress of research into exosomes and their involvement in the pathogenesis, diagnosis, and treatment of ACD and provides ideas for exploring new diagnostic and treatment methods for this disease.
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KEYWORD
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Allergic contact dermatitis, exosomes, immunoregulation, inflammation
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